The Metabolic fate of ethyl O-[N-(p-carboxyphenyl)-carbamoyl] mycophenolate (CAM)‚ a new anticancer agent‚ in experimental animals. The pharmacokinetics of a new anti-tumor agent i.e. ethyl o- [N-(p- carboxy phenyl)- carbamoyl] Mycophenolate (CAM) was studied in mice by using 14 c-labeled CAM and also metabolic differences were studied in species like rats‚ mice‚ rabbits‚ guinea pigs & dogs. The
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(2010) is a level IV cohort study that aims to evaluate whether a nutritional program is able to balance the metabolic effects of menopause in a large sample of perimenopausal women. The study evaluated 301 nondiabetic perimenopausal women before a nutritional program designed to improve cardiovascular disease risk and 262 nondiabetic perimenopausal women after
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Periwinkle (Catharantus roseus) and Serpentina (Andrographis paniculata) plant extracts as an Anti-diabetic Drug on Alloxan-induced Albino Rats (Rattus norvegicus) Life Science Researchers: *Angelou M. Dela Cruz Taze Jared D. Abubo Angelica V. Calma Zeus Jovette M. Manalastas Joab C. Fernando Lanz Martin Solano Gian Paulo D. Magnaye Jovanni Estrada Nesly Santos Wilbern Apat Monica Maddara Research Adviser: Mr. Earl Francis C. Merilles Research Consultant: Mr. Raymond Jay
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polyunsaturated fatty acid-rich liquid oils. This blending produced fat products of zero-trans fatty acid content and melting points below the human body temperature‚ so that they can be digested easily. The new blended products were fed to male albino rats (Charles Foster strain); the coefficients of digestibilities were 94.2% for palmstearin and rapeseed oil blend‚ 95.1% for palmstearin and sunflower oil blend‚ and 96.2% for palmstearin and soybean oil blend‚ which were somewhat better than the digestibility
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claims apple cider vinegar can now be found in many health shops around the country. So how accurate are these claims? Most of the claims have been based purely on studies conducted in animal studies.The claims regarding diabetes has only been seen in rat models. A study was conducted looking at the lipid profiles
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by temporarily shutting off nonessential‚ at the moment‚ immune and digestive systems. When the body is ready for a challenge‚ heart rate increases‚ blood pressure rises and glucose production intensifies to supply large amounts of energy. These metabolic changes are caused by release of stress hormones (catecholamine and epinephrine) by adrenal glands. When stressful situation goes away‚ body returns to its normal state. But if the stress is chronic‚ the mechanism remains activated and organism is
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Application of statistics in Pharmaceutical industry * * * Bookmark Although the advancement of medicine has prolonged and improved the life of many people over the years‚ it is important to remember that it is not an exact science. While some treatments do seem to offer a complete ’cure’ for any particular ailment universally‚ the vast majority of medicinal treatments do not. As such‚ it is important that statistics are used in medicine in order to justify the development and subsequent
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Filtration Activity 1: Effect of Arteriole Diameter on Glomerular Filtration 1. Compare this data with your baseline data. How did increasing the afferent arteriole radius affect glomerular filtration rate? >>Increasing the afferent arteriole radius pushed the glomerular pressure‚ the glomerular filtration rate‚ and the volume of urine to be higher than the baseline data. Increasing the afferent arteriole radius increased the glomerular filtration rate. 2. Under these conditions
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VIAGRA® (sildenafil citrate) Tablets DESCRIPTION VIAGRA®‚ an oral therapy for erectile dysfunction‚ is the citrate salt of sildenafil‚ a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Sildenafil citrate is designated chemically as 1-[[3-(6‚7-dihydro-1-methyl-7-oxo-3-propyl-1Hpyrazolo[4‚3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate and has the following structural formula: O C H 3C H 2 O CH3 N HN N
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catecholamine release and reduction of cerebral metabolic rate Cerebral hypoxic injury is known to be associated with a massive catecholamine increase in central and peripheral norepinephrine concentrations are commonly seen with cerebral hypoxic injury. Catecholamines may impoverish outcome from cerebral ischemia‚ possibly by stimulating central _2-receptors (Figure 2.20). Neuronal damages are results of icreased norepinephrine due to the elevation of metabolic demand and alteration of blood flow to surrounding
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