The earliest documented occurrence of FOP dates back to the 17th and 18th centuries, where doctors were confused by this mysterious disorder. In 1692, a French physician named Guy Patin encountered a patient who had FOP and wrote in his writings about a woman who he thought “turned …show more content…
FOP is a disorder that causes a person’s muscle and connective tissue, such as ligaments and tendons, to slowly be replaced by bone. This is done through a process known as ‘ossification’, where bone forms outside of the skeleton. This constrains the affected person’s ability to move. For some people the bone growth is a rapid event. While others experience a gradual progression of bone formation. Currently, doctors cannot predict the rate of growth. The vert first sign of the disorder, which are visible at birth, are the malformation of the person’s toes, which present as short, bent, and at times curved. Usually before the person reaches the age of ten, they experience inflammation and sometimes painful swelling, commonly in their back and shoulder area and at times their head and scalp. These usually take on the appearance of large tumors. If the person has experienced any physical trauma might trigger episodes of inflammation and swelling that is followed by an increase in ossification in the area of injury. At first the areas that have been affected can be red and painful, potentially hot to the touch, which are common symptoms of inflammation. Parents of children with FOP have also noted that their children experience fever in addition to these symptoms. Parents can also be the ones who are infecting their