Sickle-Cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin. These hemoglobin molecules tend to aggregate after unloading oxygen forming long‚ rod-like structures that force the red cells to assume a sickle shape. Unlike normal red cells‚ which are usually smooth and malleable‚ the sickle red cells cannot squeeze through small blood vessels. When the sickle cells block small blood vessels‚ the organs are deprived of blood and oxygen. This leads to periodic
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MARK DEFOREST HIT-130-WK1D1-ASSIGNMENT ------------------------------------------------- Complete Proofreading Exercise #1 (page 208) (I have very little idea what to do‚ but I gave it a try‚ How did I do?) MARK 5/22/2013 | DEATH SUMMARY Patient Name: Teiko Sun Patient ID: 469011 Admitted: 08/17/2013 Deceased: 08/20/2013 at 4:30 p.m. Consultations: None. Procedures: Proctoscopy. This 75-year-old Asian female was admitted through the ER with acute massive rectal bleeding of
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Conclusion 1 Based on what you know about blood‚ why would having a sickle cell anemia crisis result in a reduced red blood cell count‚ an elevated white blood cell count‚ and a reduced hematocrit? There’s a reduced RBC count‚ elevated WBC count‚ and a reduced hematocrit because of the shape of the RBC. The sickle cell anemia causes the RBC to have a different shape; a crescent and rigid shape and there are not a lot of them. So because of that‚ there’s more WBC and a reduced hematocrit. Also‚ the
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A mutation can simply be put as abrupt change in the genotype of an organism that is not the result of recombination. A gene mutation is a permanent change in the DNA sequence that makes up a gene. Mutations range in size from a single DNA building block (DNA base) to a large segment of a chromosome. Gene mutations occur in two ways: they can be inherited from a parent or acquired during a person’s lifetime. Mutations that are passed from parent to child are called hereditary mutations or germ
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EVALUATION OF ANAEMIA IN THE GHANAIAN CHILD. GROUP B2. MEMBERS • • • • • CEPHAS AVOKA CHRISTIANA BAFFOUR AWUAH IBIRONKE AZEEZAT AKUA ADOBEA AYISI KWAKU AYISI-TETE Aim & Objectives Aim: Increase knowledge of students on evaluation of anemia Objectives: 1.Understand the various definitions‚ classifications and aetiology of anaemia 2.Easily identify a child with anaemia 3.To interpret haematological results 4.Successfully treat anaemia 5.Identify with the causes‚ diagnosis
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Paul V. 14-UC-1882 UC-38 Dr. Alma Nacua Autoimmune Disease Causes Effects Ankylosing spondylitis Ankylosing spondylitis has no known specific cause‚ though genetic factors seem to be involved. In particular‚ people who have a gene called HLA-B27 are at significantly increased risk of developing
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Systemic Lupus Erythematosus (SLE) is an autoimmune heterogenous disease‚ meaning it is caused by many genes and alleles and variations of those genes. According to the Journal of Rare Diseases‚SLE is characterized by the presence of autoantibodies against nuclear antigens (1). An estimated 1 per 1000 individuals are affected overall‚ qualifying SLE as a rare disease. Females are more affected at a female to male ratio of 10:1. Researchers believe that‚ as many females become susceptible during pregnancy
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Immunosuppressive Immunosuppressive drugs drugs Immunosuppressive Immunosuppressive Drugs Drugs O tli Outline of Lecture Topics: fL t T i 1. Immune Responses 1 Immune Responses 2. Classes of Immunosuppressive Drugs Bertram G Katzung‚ 11th Edition. Chapter 55‚ pp 963-986. Immunosuppressive Immunosuppressive Drugs drugs g 1. IMMUNE RESPONSES A. Normal Immune Responses Protect host from infections‚ pathogens‚ and to eliminate disease. Protection from infection and disease is provided by the
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Blood Quiz 1. The most abundant leukocytes are _____. a. Basophils b. Monocytes c. Lymphocytes d. Neutrophils – ANS 2. Platelet formation is regulated by ______. e. Interleukin-2 f. Thrombopoietin - ANS g. Plasmin h. Erythropoietin 3. In a centrifuged sample of blood‚ what makes up the buffy coat? i. Plasma j. WBC and platelets - ANS k. RBC l. Platelets only 4. What is hematocrit a measure of? Hematocrit
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non-immune-mediated source of disease. Mechanisms that can cause non-immune mediated thrombocytopenia include hemorrhage‚ bone marrow suppression by radiation or chemotherapy‚ platelet consumption and others. Rare causes of thrombocytopenia include hemolytic uremia‚ inherited thrombocytopenia‚ and bone marrow
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